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Updated: Jun 27, 2025

CD Spectroscopy to Study DNA-Protein Interactions
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Persistent Chirality-Induced Spin-Selectivity Effect in Circular Helix Molecules.

Song Chen1, Ruqian Wu2, Hua-Hua Fu1,3

  • 1School of Physics and Wuhan National High Magnetic Field Center, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.

Nano Letters
|May 6, 2024
PubMed
Summary
This summary is machine-generated.

Researchers discovered persistent chirality-induced spin selectivity (CISS) currents in DNA and proteins, a new equilibrium effect (PCISS) distinct from traditional CISS, enabling pure spin current generation.

Keywords:
Berry phasechirality-induced spin selectivitychirality-locked pure spin currentcircular helix moleculespersistent CISS effect

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Area of Science:

  • Molecular Biophysics
  • Condensed Matter Physics
  • Organic Electronics

Background:

  • Chirality-induced spin selectivity (CISS) and spin currents are crucial in chiral molecules.
  • Traditional CISS arises from nonequilibrium transport, spin-orbit coupling (SOC), and broken symmetries.

Purpose of the Study:

  • To demonstrate persistent CISS currents in circular DNA and 310-helix proteins.
  • To introduce a novel equilibrium CISS effect (PCISS) independent of external magnetic flux.

Main Methods:

  • Experimental investigation of transport properties in circular single-stranded DNAs.
  • Characterization of spin currents in 310-helix proteins.

Main Results:

  • Generation of persistent CISS currents in circular DNA and 310-helix proteins.
  • Observation of a new equilibrium CISS effect (PCISS) distinct from traditional CISS.
  • PCISS is independent of external magnetic flux and SOC origin (chirality-driven or heavy-metal substrates).

Conclusions:

  • Established a novel paradigm for generating chirality-locked pure spin currents.
  • PCISS offers an efficient method for creating pure spin currents in equilibrium.
  • The findings advance the understanding of CISS effects in biological and synthetic chiral systems.