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Updated: Jun 13, 2026

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
Published on: June 24, 2013
Applying 3D ED/MicroED workflows toward the next frontiers
Mahira Aragon1, Sarah E J Bowman2, Chun Hsing Chen3
1Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave, New York, New York 10027, USA.
Abstract:
We report on the latest advancements in Microcrystal Electron Diffraction (3D ED/MicroED), as discussed during a symposium at the National Center for CryoEM Access and Training housed at the New York Structural Biology Center. This snapshot describes cutting-edge developments in various facets of the field and identifies potential avenues for continued progress. Key sections discuss instrumentation access, research applications for small molecules and biomacromolecules, data collection hardware and software, data reduction software, and finally reporting and validation. 3D ED/MicroED is still early in its wide adoption by the structural science community with ample opportunities for expansion, growth, and innovation.

