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Published on: April 10, 2021
The Development and Opportunities of Predictive Biotechnology
Bettina M Nestl1,2, Bernd A Nebel2, Verena Resch2
1Joint working group on biotransformations of the Association for General and Applied Microbiology VAAM, the Society for Chemical Engineering, Biotechnology DECHEMA, Theodor-Heuss-Allee 25, 60486, Frankfurt, Germany.
Advancements in AI tools, including automated genome annotation and protein structure prediction (e.g., AlphaFold2), are accelerating progress in biocatalysis and biotechnology. These innovations offer significant opportunities for both academia and industry to drive further development in the bioeconomy.
Area of Science:
- Biotechnology
- Bioeconomy
- Computational Biology
Background:
- The bioeconomy is rapidly advancing, integrating new process chains and production methods.
- Progress is increasingly supported by sophisticated prediction tools developed by academia and industry.
- Tools like AlphaFold2 and RoseTTAFold have significantly improved protein structure prediction.
Purpose of the Study:
- To highlight the growing impact of Artificial Intelligence (AI) in biocatalysis and biotechnology.
- To emphasize the synergistic opportunities for academia and industry in leveraging AI for accelerated advancements.
- To underscore the interdisciplinary nature of biotechnology and its potential to benefit from AI integration.
Main Methods:
- Review of recent advancements in bioeconomy process chains.
- Identification and discussion of popular prediction tools in bioinformatics.
- Analysis of the emerging trend of AI-based tool development for biotechnology.
Main Results:
- Automated genome annotation and protein structure prediction tools are gaining widespread adoption.
- A significant increase in the development and application of AI-based tools for biocatalysis and biotechnology is observed.
- These AI tools are enhancing the capabilities of both academic research and industrial applications.
Conclusions:
- AI-driven tools represent a transformative opportunity for the field of biotechnology.
- Collaboration between academia and industry is crucial for maximizing the benefits of these AI advancements.
- The integration of AI is poised to further accelerate innovation and growth within the bioeconomy.
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