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Relationship between visit-to-visit blood pressure variability and depressive mood in Korean primary care patients

Ga Hee Lee1, Jung Ah Lee2, Sung Sunwoo3

  • 1Department of Family Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Asan, Gyeonggi-do, South Korea.

BMC Primary Care
|May 7, 2024
PubMed

Insights

Depressive mood is linked to higher blood pressure variability (BPV) in Korean primary care patients on medication. This association suggests a potential increase in cardiovascular risk, highlighting the need for monitoring BPV in patients with depressive symptoms.

Area of Science:

  • Cardiology
  • Psychiatry
  • Primary Care Medicine

Background:

  • High blood pressure variability (BPV) is a significant risk factor for cardiovascular disease (CVD), potentially more so than average blood pressure.
  • Depressive mood is a prevalent condition encountered in primary care settings.
  • Understanding the interplay between depressive mood and BPV is crucial for managing cardiovascular risk in primary care populations.

Purpose of the Study:

  • To investigate the association between depressive mood and high visit-to-visit systolic blood pressure variability (SBPV) in Korean primary care patients.
  • To determine if depressive mood is an independent predictor of high SBPV in this population.

Main Methods:

  • A prospective cohort study (Family Cohort Study in Primary Care - FACTS) involving Korean primary care patients from April 2009 to November 2017.
  • Depressive mood was defined as a score ≥21 on the Korean-type Center for Epidemiologic Studies Depression scale.
  • Visit-to-visit SBPV was analyzed using standard deviation, coefficient of variation, variation independent of mean, and average real variability, with logistic regression used for association analysis.

Main Results:

  • Among 371 participants, 11.6% exhibited depressive mood.
  • Older age was associated with high SBPV (OR: 1.04, 95% CI: 1.01-1.07).
  • Patients with depressive mood taking antihypertensive medication showed a nearly threefold increased risk of high SBPV (OR: 2.95, 95% CI: 1.06-8.20) compared to those without depressive mood.

Conclusions:

  • Depressive mood is significantly associated with high visit-to-visit SBPV among primary care patients receiving antihypertensive treatment.
  • This finding suggests that depressive symptoms may contribute to increased cardiovascular risk through elevated blood pressure fluctuations.
  • Primary care physicians should consider monitoring BPV in patients with depressive symptoms and implement targeted interventions.
Abstract

Keywords:
Blood pressureBlood pressure variabilityDepressive moodPrimary careVisit-to-visit blood pressure variability

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