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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Related Experiment Video

Updated: Jun 26, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Structured clinical interview for diagnosing obsessive-compulsive spectrum disorders.

Christine Lochner1, Karen T Maré2, Dan J Stein2

  • 1SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, University of Stellenbosch, South Africa.

Comprehensive Psychiatry
|May 8, 2024
PubMed
Summary
This summary is machine-generated.

A new diagnostic interview, the SCID-OCSD, helps identify obsessive-compulsive spectrum disorders (OCSDs) in adults with OCD. This tool aids in diagnosing comorbid conditions, improving treatment planning and research for these complex disorders.

Keywords:
DSM-5ICD-11Obsessive-compulsive disorderObsessive-compulsive spectrum disordersStructured diagnostic interview

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Established diagnostic interviews exist for common mental disorders.
  • Specialty clinics, like those for Obsessive-Compulsive Disorder (OCD), benefit from focused diagnostic tools.
  • The Semi-Structured Clinician-Administered Interview for Obsessive-Compulsive Spectrum Disorders (SCID-OCSD) was developed for DSM-5/ICD-11 criteria.

Purpose of the Study:

  • To introduce the SCID-OCSD for detailed assessment of OCSDs.
  • To evaluate the SCID-OCSD's implementation in adults with primary OCD at a specialized unit.

Main Methods:

  • Adult patients with primary OCD and moderate-to-severe symptoms (Yale-Brown Obsessive-Compulsive Severity scale score ≥ 14) were interviewed.
  • The SCID-OCSD assesses OCD, related disorders, impulse-control disorders, and compulsive-impulsive conditions.
  • Comorbid conditions included tics, eating disorders, non-suicidal self-injury, and behavioral addictions.

Main Results:

  • 101 adults with current OCD participated (37 men, 64 women).
  • 42 participants had one or more current/past comorbid OCSDs.
  • Most common OCSDs were excoriation disorder (n=16) and body dysmorphic disorder (n=14).
  • History of non-suicidal self-injury (n=9) and comorbid tics (n=6) were also reported.

Conclusions:

  • The SCID-OCSD can aid in diagnosing the full spectrum of OCSDs within OCD clinics.
  • This facilitates improved treatment planning for patients with OCD and related conditions.
  • The SCID-OCSD supports further research into these complex and often comorbid disorders.