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Related Experiment Video

Updated: Jun 26, 2025

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

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Published on: September 5, 2011

Matthew-Wood Syndrome in Monochorionic, Diamnionic Twins.

Irina Geiculescu¹, Matthew A Saxonhouse², Laurie Demmer³

¹Department of Pediatrics, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States.

Journal of Pediatric Genetics

|May 9, 2024

Summary

This summary is machine-generated.

Matthew-Wood syndrome, a rare genetic disorder, was identified in monochorionic twin females. This case highlights the syndrome

Keywords:

Matthew-Wood syndrome twins

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Area of Science:

Medical Genetics
Developmental Biology
Pediatric Medicine

Background:

Matthew-Wood syndrome is a rare genetic disorder.
It is characterized by diaphragmatic defects, pulmonary hypoplasia, microphthalmia/anophthalmia, and cardiac defects.
Most cases are lethal, with few infants surviving past a few years.

Purpose of the Study:

To review and discuss Matthew-Wood syndrome.
To present a unique case of the syndrome in monochorionic, diamnionic twin females.
To add to the limited understanding of this rare condition.

Main Methods:

Literature review of Matthew-Wood syndrome.
Case report of monochorionic, diamnionic twin females with the syndrome.
Discussion of clinical presentation and implications.

Main Results:

The syndrome presented in monochorionic, diamnionic twin females.
This is the first reported case of Matthew-Wood syndrome in twins.
The review consolidates existing knowledge and presents a novel case.

Conclusions:

Matthew-Wood syndrome can occur in twins, a previously unreported occurrence.
This case provides valuable insights into the variability and presentation of the syndrome.
Further research is needed to understand the genetic and developmental factors in twin presentations.