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Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

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Managing children with frequent respiratory infections and associated wheezing: a preliminary randomized study with a

Maria Angela Tosca1, Attilio Varricchio2, Irene Schiavetti3

  • 1Allergy Center, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Allergologia Et Immunopathologia
|May 9, 2024
PubMed

Insights

This preliminary study found that a nasal spray containing lactoferrin, dipotassium glycyrrhizinate, carboxymethyl-beta-glucan, and vitamins C and D3 (Saflovir) reduced respiratory infections (RIs) and wheezing episodes in preschoolers.

Area of Science:

  • Pediatrics
  • Immunology
  • Respiratory Medicine

Background:

  • Preschoolers are prone to respiratory infections (RIs) and associated wheezing.
  • Type 2 immune responses may increase susceptibility to RIs and wheezing.
  • Non-pharmacological interventions are explored as complementary therapies for RIs.

Purpose of the Study:

  • To evaluate the efficacy and safety of a novel multi-component nasal spray for frequent RIs and wheezing in preschoolers.
  • To assess the impact of the nasal spray as an add-on therapy to standard care.

Main Methods:

  • A randomized controlled trial involving preschoolers with frequent RIs and wheezing.
  • Participants received either the multi-component nasal spray (Saflovir) or standard therapy for 3 months.
  • Outcomes measured included RI and wheezing episode frequency, medication use, and clinical severity.

Main Results:

  • Children using the multi-component nasal spray experienced significantly fewer RIs compared to the control group (P=0.01).
  • Add-on nasal spray treatment led to reduced use of beta-2 agonists for wheezing relief (P=0.029).

Conclusions:

  • This preliminary study suggests the multi-component nasal spray is a safe and effective add-on therapy for reducing RIs in preschoolers.
  • The nasal spray may decrease the incidence of respiratory infections and the need for symptomatic treatments for wheezing in children.
Abstract

Keywords:
beta-glucansglycyrrhetic acidlactoferrinmedications’ usepreschoolersrespiratory infectionssymptomsvitamin Cvitamin D3wheezing

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