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Third molar agenesis in individuals with supernumerary teeth
Luca Friedli1, Eva Henninger1, Miltiadis A Makrygiannakis2
1Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern, Bern, Switzerland.
Orthodontics & Craniofacial Research
|May 9, 2024
Summary
Supernumerary teeth did not significantly impact third molar agenesis likelihood or severity. However, bilateral third molar agenesis was less common in individuals with supernumerary teeth compared to controls.
Area of Science:
- Dental Development
- Human Genetics
- Oral Pathology
Background:
- Third molar agenesis is a common developmental anomaly.
- Supernumerary teeth are extra teeth that form in the dental arch.
- The relationship between these two conditions is not fully understood.
Purpose of the Study:
- To investigate the association between third molar agenesis and the presence of supernumerary teeth.
- To determine if supernumerary teeth influence the prevalence or severity of third molar agenesis.
Main Methods:
- Retrospective review of dental records from 380 white-European individuals.
- Comparison between a group with non-syndromic permanent supernumerary teeth and an age/sex-matched control group.
- Analysis of panoramic radiographs to identify tooth sequences and agenesis.
Main Results:
- No significant difference in the prevalence or severity of third molar agenesis between groups.
- Third molar agenesis occurred in 14.7% of individuals in both the supernumerary and control groups.
- The ratio of bilateral to unilateral third molar agenesis was significantly lower in the supernumerary group (1.0) compared to controls (3.7).
Conclusions:
- Supernumerary teeth do not significantly alter the likelihood or severity of third molar agenesis.
- Bilateral third molar agenesis is less prevalent in individuals with supernumerary teeth.
- These findings suggest distinct developmental pathways or influences for these dental anomalies.
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