Related Experiment Video
Updated: Jun 26, 2025
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Emerging Antifungal Resistance in Fungal Pathogens
Sui Ting Hui1, Hugh Gifford2, Johanna Rhodes1,3
1MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Purpose Of Review:
Over recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and animals. Yet this problem is compounded by emerging antifungal drug resistance in pathogenic species. Resistance develops over time when fungi are exposed to drugs either in the patient or in the environment.
Recent Findings:
Novel resistant variants of fungal pathogens that were previously susceptible are evolving (such as Aspergillus fumigatus) as well as newly emerging fungal species that are displaying antifungal resistance profiles (e.g. Candida auris and Trichophyton indotineae).
Summary:
This review highlights the important topic of emerging antifungal resistance in fungal pathogens and how it evolved, as well as how this relates to a growing public health burden.
