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Related Experiment Videos

Bleeding from stress gastritis. Has prophylactic pH control made a difference?

L F Martin, G M Larson, D E Fry

    The American Surgeon
    |April 1, 1985
    PubMed
    Summary
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    Standard prophylaxis for acute erosive gastritis (AEG) in critically ill patients did not reduce bleeding incidence. Inadequate prophylaxis was common, highlighting the need for consistent treatment to reduce complications.

    Area of Science:

    • Critical Care Medicine
    • Gastroenterology
    • Surgical Outcomes

    Background:

    • Acute erosive gastritis (AEG) bleeding is a concern in critically ill patients.
    • Standard prophylaxis involves controlling intragastric pH with antacids or H2-receptor antagonists.

    Purpose of the Study:

    • To evaluate the effectiveness of prophylactic pH control in reducing AEG bleeding incidence.
    • To compare morbidity, mortality, and risk factors before and after implementing standard prophylaxis.

    Main Methods:

    • Retrospective analysis of AEG bleeding incidence in critically ill patients.
    • Comparison of preprophylaxis and postprophylaxis eras on trauma and surgical services.

    Main Results:

    • AEG bleeding incidence remained constant at 2.3% in both eras.

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  • Fewer patients required surgery postprophylaxis (1 vs 3), but transfusion needs were similar.
  • Inadequate prophylaxis was noted in over half of bleeding patients.

    • Conclusions:

    • Routine pH control did not significantly alter AEG bleeding rates.
    • Inadequate prophylaxis is a major issue, impacting treatment effectiveness.
    • While complications may decrease with consistent prophylaxis, AEG bleeding is unlikely to be eliminated.