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Incorporating versus coating antimicrobials for polymethyl methacrylate: A systematic review
Izabela Ferreira1, Diego Morita Gomes da Costa2, Andrea Cândido Dos Reis3
1Predoctoral student, Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo (USP), Ribeirão Preto, Brazil.
The Journal of Prosthetic Dentistry
|May 10, 2024
Summary
Incorporating and coating polymethyl methacrylate (PMMA) with antimicrobial agents effectively enhances its antimicrobial action. Combining both methods provides superior results against microbial accumulation in denture bases.
Area of Science:
- Biomaterials Science
- Dental Materials
- Microbiology
Background:
- Polymethyl methacrylate (PMMA) denture bases can harbor microorganisms, leading to oral and systemic diseases.
- Antimicrobial incorporation and coating techniques aim to prevent microbial accumulation on PMMA.
Purpose of the Study:
- To systematically review the effectiveness of antimicrobial incorporation and coating techniques on PMMA.
- To determine if these methods confer antimicrobial action on PMMA denture bases.
Main Methods:
- Systematic review following PRISMA guidelines.
- Searched SCOPUS, PubMed/Medline, EMBASE, and Science Direct databases.
- Risk of bias assessed using the Joanna Briggs Institute (JBI) tool.
Main Results:
- 32 studies were included after screening 970 articles.
- Both incorporation and coating techniques demonstrated antimicrobial activity.
- Incorporation was more prevalent than coating, but both were effective.
Conclusions:
- Antimicrobial incorporation and coating are effective strategies for PMMA.
- Combining both techniques enhances antimicrobial activity more than individual methods.
