Activity of acid phosphatase in resting and mitogen-stimulated human peripheral blood lymphocytes

Activity of acid phosphatase was found to be higher in T than in non-T cells of human peripheral blood lymphocytes. The T cell mitogen PHA induced an increase in the magnitude of acid phosphatase activity, while the B cell mitogen LPS was not able to produce any effect on acid phosphatase activity. Acid phosphatase activity in lymphocytes correlated with their spontaneous proliferative activity.