Related Experiment Video
Updated: Aug 2, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Narrative review of radiofrequency ablation applications in peripheral nerves
Alaa Abd-Elsayed1, Christopher L Robinson2, Theodore Peters1
1Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Background And Objective:
Chronic pain is a pervasive and often-complex condition that can severely detract from an individual's quality of life. When conservative measures of treatment fail, radiofrequency ablation (RFA) has emerged as a potential alternative. This narrative review subsequently explores recent advancements in the use of RFA on peripheral nerves as a means of attenuating chronic pain and providing relief to patients.
Methods:
A comprehensive literature search was conducted on the PubMed database using the keywords "Radiofrequency", "Ablation", "Pain", "Chronic", "Peripheral", and "Nerve". The search focused on articles published between 2018 to 2023 that discussed an application of RFA in a peripheral nerve. In total, 30 articles were selected for inclusion in this review.
Key Content And Findings:
Results indicate the successful use of RFA in an array of chronic pain conditions and anatomical sites. Applications include the treatment of trigeminal neuralgia (TN), occipital neuralgia, cluster headaches, knee pain derived from osteoarthritis (OA), hip pain, abdominal pain associated with pancreatic cancer, and several other chronic pain conditions.
Conclusions:
These findings suggest RFA is a viable option for reducing patient's pain scores and improving quality of life. Future research should build off extensive case reports/series with double-blind, randomized controlled studies to further investigate anecdotal successes.

