Complete genome sequences of Campylobacter jejuni subsp. jejuni strain P4549 isolated from an asymptomatic rhesus
1Surveillance/Diagnostic Laboratory, Office of Scientific Coordination, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, USA.
Abstract:
Campylobacter jejuni subsp. jejuni is a leading bacterial cause of human gastroenteritis. C. jejuni strain P4549 was isolated from an asymptomatic rhesus monkey, Macaca mulatta. We report the genome sequences have a circular chromosome of 1,729,940 bp and two plasmids of 50,482 bp and 7,259 bp, respectively.
Insights
Campylobacter jejuni subspecies jejuni causes human gastroenteritis. Researchers sequenced the genome of C. jejuni strain P4549 from a rhesus monkey, revealing its chromosome and plasmid structures.
Area of Science:
- Microbiology
- Genomics
- Veterinary Science
Background:
- Campylobacter jejuni subspecies jejuni is a primary bacterial pathogen responsible for human gastroenteritis worldwide.
- Understanding the genomic makeup of C. jejuni strains is crucial for tracking its transmission and developing control strategies.
Purpose of the Study:
- To report the complete genome sequence of Campylobacter jejuni strain P4549.
- To characterize the genomic structure, including chromosomal and plasmid DNA, of this strain isolated from a non-human primate.
Main Methods:
- Whole-genome sequencing of Campylobacter jejuni strain P4549.
- Bioinformatic analysis to assemble and annotate the circular chromosome and plasmids.
Main Results:
- The genome consists of a single circular chromosome of 1,729,940 base pairs.
- Two circular plasmids were identified with sizes of 50,482 bp and 7,259 bp, respectively.
Conclusions:
- The genome sequencing provides a foundational resource for studying Campylobacter jejuni P4549.
- This genomic data can aid in understanding the evolution and host-pathogen interactions of C. jejuni, particularly in zoonotic contexts.
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