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Updated: Jun 26, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
The role of automated insulin delivery technology in diabetes
Charlotte K Boughton1, Roman Hovorka2
1Wellcome-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge, UK. cb2000@medschl.cam.ac.uk.
Abstract:
The role of automated insulin delivery systems in diabetes is expanding. Hybrid closed-loop systems are being used in routine clinical practice for treating people with type 1 diabetes. Encouragingly, real-world data reflects the performance and usability observed in clinical trials. We review the commercially available hybrid closed-loop systems, their distinctive features and the associated real-world data. We also consider emerging indications for closed-loop systems, including the treatment of type 2 diabetes where variability of day-to-day insulin requirements is high, and other challenging applications for this technology. We discuss issues around access and implementation of closed-loop technology, and consider the limitations of present closed-loop systems, as well as innovative approaches that are being evaluated to improve their performance.
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