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Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

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Injectable 2D Material-Based Sensor Array for Minimally Invasive Neural Implants.

Jejung Kim¹, Juyeong Hong¹, Kyungtai Park¹

¹School of Electrical and Electronic Engineering, Yonsei University, Seoul, 03722, Republic of Korea.

Advanced Materials (Deerfield Beach, Fla.)

|May 14, 2024

Summary

This summary is machine-generated.

Researchers developed an injectable brain sensor array for minimally invasive diagnosis and treatment of neurological conditions. This new device monitors brain activity, temperature, and pressure, offering a less invasive alternative to traditional implants.

Keywords:

2D materials MoS2 graphene neural recording sensors

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Last Updated: Jun 26, 2025

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Area of Science:

Biomedical Engineering
Neuroscience
Materials Science

Background:

Conventional intracranial implants require invasive surgery and offer limited data.
Existing devices face challenges in achieving conformal contact with the brain surface.

Purpose of the Study:

To develop a minimally invasive, injectable multi-modal sensor array for brain monitoring and treatment.
To overcome the limitations of conventional bulky and invasive brain implants.

Main Methods:

Designed an injectable sensor array using a mesh structure with graphene electrodes and MoS2-based sensors.
The mesh structure allows the contracted device to spread for conformal cortical contact after injection.
Demonstrated device injection and function in a rabbit model.

Main Results:

The sensor array successfully detected epileptic discharges on the cortex.
Electrical stimulation from the array mitigated epileptic activity.
The device continuously monitored intracranial temperature and pressure.

Conclusions:

The injectable multi-modal sensor array offers a promising minimally invasive approach for brain disease diagnosis and treatment.
This technology has potential for implanting various functional devices with reduced surgical invasiveness.
The study highlights a significant advancement in neurotechnology for managing brain conditions.