Detection of epinephrine using a K₂Fe₄O₇ modified glassy carbon electrode

Area of Science:

• Electrochemistry
• Materials Science
• Biosensing

Background:

• Iron-based electrochemical catalysts are increasingly used in biosensors due to their biocompatibility and affordability.
• Developing efficient modified electrodes is crucial for sensitive and selective analyte detection.

Purpose of the Study:

• To prepare a potassium ferrite (K2Fe4O7) modified glassy carbon electrode (GCE) for electrochemical epinephrine (EP) detection.
• To evaluate the analytical performance of the K2Fe4O7/GCE for EP detection.

Main Methods:

• Electrochemical synthesis of potassium ferrite (K2Fe4O7) on a glassy carbon electrode (GCE).
• Electrochemical detection of epinephrine using cyclic voltammetry and differential pulse voltammetry.
• Assessment of selectivity against common interferents like ascorbic acid (AA) and uric acid (UA).

Main Results:

• The K2Fe4O7/GCE exhibited a wide linear range for EP detection from 2 μM to 260 μM.
• A low detection limit of 0.27 μM (S/N = 3) was achieved for EP.
• The modified electrode showed high selectivity for EP over AA and UA, along with good reproducibility and stability.

Conclusions:

• The K2Fe4O7/GCE is a promising electrochemical sensor for sensitive and selective epinephrine detection.
• The developed electrode offers a cost-effective and efficient platform for biosensing applications.
• Further research can explore its application in complex biological samples.