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Updated: Jun 26, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Cloud-based large-scale curation of medical imaging data using AI segmentation.

Vamsi Krishna Thiriveedhi1, Deepa Krishnaswamy1, David Clunie2

  • 1Brigham and Women's Hospital, Boston, MA.

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|May 15, 2024
PubMed
Summary

Cloud computing enables efficient, large-scale medical image analysis. This study used cloud resources to analyze over 126,000 lung screening CT scans, completing the task in hours at a low cost.

Keywords:
AIcloud computingcomputed tomographyimage segmentationradiomics

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Cloud Computing

Background:

  • Medical imaging AI requires significant computational power, often exceeding on-premises capabilities.
  • Cloud computing offers scalable and economical solutions for demanding AI tasks.
  • Few studies evaluate cloud price/performance for medical image analysis.

Approach:

  • Evaluated NCI CRDC Cloud Resources (Terra and Seven Bridges) for AI-based curation of National Lung Screening Trial (NLST) CT images.
  • Performed automatic image segmentation and radiomics feature extraction on >126,000 CT volumes using TotalSegmentator and pyradiomics.
  • Utilized over 21,000 Virtual Machines (VMs) for rapid analysis.

Key Points:

  • Analysis completed in under 9 hours using cloud resources, compared to an estimated 522 days on a single workstation.
  • Total cost for large-scale analysis was $1,011.05.
  • Generated 9,565,554 segmentations and radiomics features for the NLST dataset.

Conclusions:

  • Cloud computing provides a cost-effective and scalable solution for large-scale medical image analysis.
  • Developed CloudSegmentator, an open-source workflow for reproducible medical image computing.
  • Offers practical recommendations for optimizing cloud resource utilization in medical imaging research.