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Polymer-based cascaded waveguide Bragg grating for blood glucose sensing.

Ruina Zhao, Hongqiang Li, Ming Han

    Optics Letters
    |May 15, 2024
    PubMed
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    This study presents a polymer-based cascaded waveguide Bragg grating (WBG) for blood glucose sensing. The novel sensor demonstrates high sensitivity and offers advantages for health management.

    Area of Science:

    • Photonics
    • Biomedical Sensing
    • Materials Science

    Background:

    • Waveguide Bragg gratings (WBGs) are crucial for biological sensing in health management.
    • Developing efficient and cost-effective glucose sensors is vital for medical treatment.

    Purpose of the Study:

    • To investigate a polymer-based cascaded WBG for blood glucose detection.
    • To analyze the impact of grating structures and periods on sensor performance.
    • To evaluate the spectral reflectance, response time, and specificity of the WBG glucose sensor.

    Main Methods:

    • Fabrication of a polymer-based cascaded WBG with crossed and bilateral grating structures.
    • Systematic analysis of grating parameters: crossed grating period, bilateral grating period, and number of grating periods.

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  • Evaluation of spectral reflectance, response time, and sensing specificity.

    • Main Results:

    • The cascaded WBG glucose sensor achieved a sensitivity of 175 nm/RIU.
    • Optimal performance was observed within a glucose concentration range of 0-2 mg/ml.
    • The sensor exhibited high integration, narrow bandwidth, and low cost.

    Conclusions:

    • Polymer-based cascaded WBG is a promising technology for blood glucose sensing.
    • The sensor design offers practical advantages for health management applications.
    • Further optimization of grating parameters can enhance sensing capabilities.