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Updated: Mar 27, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potent and Sub-Family Selective PKMYT1 Inhibitors

Yazhou Wang1, Chao Wang1, Xiaomin Wang1

  • 1Insilico Medicine Shanghai Ltd, Pudong New Area, China.

Chemmedchem
|March 26, 2026
PubMed

Keywords:
CCNE1‐amplifiedPKMYT1sulfur‐lone pair interactionthiazole

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