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Updated: Jun 26, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Laparoscopic assisted colectomy versus laparoscopic complete colectomy: a cost analysis.
Zhaoyang Zheng1, Qiang Du1, Libin Huang2,3
1Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.
Laparoscopic complete colectomy with intracorporeal anastomosis (LCC/IA) offers faster recovery and reduced blood loss compared to laparoscopic-assisted colectomy with extracorporeal anastomosis (LAC/EA) for colon cancer patients. Both methods show similar overall costs and safety profiles.
Area of Science:
- Colorectal Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Colon cancer management involves surgical resection, with laparoscopic techniques offering advantages over open surgery.
- Comparing different laparoscopic approaches, specifically intracorporeal vs. extracorporeal anastomosis, is crucial for optimizing patient outcomes and cost-effectiveness.
- Laparoscopic-assisted colectomy with extracorporeal anastomosis (LAC/EA) and laparoscopic complete colectomy with intracorporeal anastomosis (LCC/IA) are two such techniques.
Purpose of the Study:
- To compare short-term outcomes of LAC/EA versus LCC/IA in patients with non-metastatic resectable colon cancer.
- To explore the potential economic benefits and cost-effectiveness of each laparoscopic approach.
Main Methods:
- Retrospective analysis of patients undergoing laparoscopic hemicolectomy between January 2017 and March 2023.
- Propensity score matching (PSM) was employed to minimize selection bias and ensure comparable groups.
- Comparison of operative time, blood loss, incision length, postoperative recovery, complication rates, and costs.
Main Results:
- LCC/IA was associated with less intraoperative blood loss and shorter incision length compared to LAC/EA.
- Postoperative recovery, including time to first flatus and soft diet, was significantly shorter in the LCC/IA group.
- While surgical instrument costs were higher for LCC/IA, overall costs and 30-day postoperative complication rates were similar between the two groups.
Conclusions:
- Laparoscopic complete colectomy with intracorporeal anastomosis (LCC/IA) demonstrates superior short-term outcomes regarding blood loss and functional recovery.
- LCC/IA is a feasible, safe, and cost-effective surgical treatment option for non-metastatic resectable colon cancer.
- The findings support the wider adoption of LCC/IA for selected colon cancer patients.

