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Updated: Jun 26, 2025

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
Concomitant Pancreatitis and Pancreatic Neuroendocrine Tumor on MRI and 68 Ga-DOTATATE PET/CT
1From the Division of Nuclear Medicine, Department of Radiology, Temple University Health System, Fox Chase Cancer Center, Philadelphia, PA.
Abstract:
A 66-year-old woman had an episode of pancreatitis with symptoms starting in October 2023. MRI showed an enhancing soft tissue mass along the superior border of the pancreatic body, as well as signal changes in the pancreatic body and the tail consistent with pancreatitis. The 68 Ga-DOTATATE PET/CT demonstrated intense radiotracer uptake within the peripancreatic soft tissue mass, significantly greater than the spleen background. Biopsy of this peripancreatic mass revealed well-differentiated grade 1 neuroendocrine tumor. The body and tail of the pancreas showed diffusely increased 68 Ga-DOTATATE uptake but obviously lower than the peripancreatic neuroendocrine tumor, consistent with pancreatitis.
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