Related Experiment Video
Updated: May 5, 2026

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells
Published on: March 3, 2015
Screening p-hackers: Dissemination noise as bait
Federico Echenique1, Kevin He2
1Department of Economics, University of California, Berkeley, CA 94720.
Adding noise to published data can screen out false findings from data mining. This "dissemination noise" affects uninformed researchers more than those with prior hypotheses, improving research credibility.
Area of Science:
- Statistical methodology
- Research integrity
Background:
- Data mining, or p-hacking, generates spurious findings by fitting numerous statistical models.
- Uninformed researchers often fall prey to p-hacking, while informed researchers with hypotheses are less affected.
Purpose of the Study:
- To investigate the effectiveness of adding noise to data as a screening mechanism against p-hacking.
- To analyze how dissemination noise impacts different types of researchers and research credibility.
Main Methods:
- Theoretical analysis of how noise affects researchers with and without prior hypotheses.
- Asymptotic analysis as the number of observations grows large.
- Characterization of optimal noise levels in a tractable special case.
Main Results:
- Dissemination noise effectively screens out p-hacked findings by creating 'baits'.
- Uninformed researchers engaging in data mining are more susceptible to noise than informed researchers.
- As data size increases, noise achieves optimal screening asymptotically.
Conclusions:
- Dissemination noise, a privacy tool, can be repurposed to enhance research credibility by screening p-hackers.
- Optimal noise levels can be determined, balancing screening effectiveness and potential information loss.
More Related Videos
11:38High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
09:58Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems
Published on: December 8, 2017
Related Concept Videos
Leaky Scanning
Patch Clamp
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Censoring Survival Data