[Pregnancy and childbirth in a mother with active histiocytosis]

The course of pregnancy is described in a 20-year-old patient who had had active histiocytosis X since infancy. After an acute onset during the first year of life, a disseminated chronic state developed at 18 months of age which persisted until the pregnancy. Long-term therapy with 6-mercaptopurine was instituted at diagnosis and was not discontinued until the 17th week of pregnancy. The course of pregnancy, delivery and puerperium was normal except for elevated LDH, altered protein electrophoresis and anemia. The newborn showed no abnormality.