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Updates in Management of Large Hemispheric Infarct
Charlene J Ong1,2, Stefanos Chatzidakis3, Jimmy J Ong4,5
1Department of Neurology, Chobanian and Avedisian School of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Seminars in Neurology
|May 17, 2024
Summary
This review covers new management strategies for large hemispheric infarction (LHI), a severe stroke type. It highlights advancements in acute therapies, monitoring, and complication management for LHI patients.
Area of Science:
- Neurology
- Stroke Medicine
- Critical Care
Background:
- Large hemispheric infarction (LHI) affects up to 10% of supratentorial stroke patients.
- Traditional LHI management is being updated by recent research.
- Space-occupying mass effect is a significant post-LHI complication.
Purpose of the Study:
- To review current management strategies for large hemispheric infarction.
- To highlight recent advancements in acute therapies and complication mitigation.
- To integrate contemporary guidelines with clinical trial findings for LHI care.
Main Methods:
- Literature review of recent research and clinical trials on LHI management.
- Analysis of updated triage methodologies and acute treatment approaches.
- Examination of strategies for monitoring and managing LHI complications.
Main Results:
- Advancements in triage and the use of pharmacological and mechanical treatments have reshaped acute LHI care.
- Refined strategies for surveillance and mitigation of complications like mass effect are emerging.
- Contemporary guidelines and trial findings offer a comprehensive view of LHI management.
Conclusions:
- Evolving strategies are crucial for effective management of large hemispheric infarction.
- Updated approaches to acute care, monitoring, and complication management improve patient outcomes.
- This review provides a comprehensive overview of the current landscape of LHI care.
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