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Gray Matter Alterations in Panic Disorder: A Voxel-Wise Meta-Analysis
Anguang Pan1, Shaojie Liu2, Shijun Hu1
1Department of Radiology, Xishan Hospital, the Seventh People's Hospital of Wenzhou, Wenzhou, Zhejiang, China.
Psychiatry and Clinical Psychopharmacology
|May 20, 2024
Summary
Gray matter changes in the brain are linked to panic disorder. This meta-analysis found specific alterations in regions like the amygdala and cingulate gyrus, suggesting their importance in panic disorder neurobiology.
Area of Science:
- Neuroscience
- Psychiatry
- Neuroimaging
Background:
- Gray matter alterations are implicated in the pathophysiology of panic disorder.
- Existing literature lacks consistent conclusions regarding these changes.
- A comprehensive meta-analysis is needed to clarify the role of gray matter in panic disorder.
Conclusions:
- Gray matter alterations in the amygdala, cingulate, and frontal regions are crucial to panic disorder neurobiology.
- These findings highlight specific brain regions potentially involved in the disorder's pathophysiology.
- Further research is recommended to confirm these observed gray matter patterns in panic disorder.
