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Updated: Jun 26, 2025

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

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Purinergic Signaling Drives Multiple Aspects of Rotavirus Pathophysiology

Kristen A Engevik, Francesca J Scribano, J Thomas Gebert

    Biorxiv : the Preprint Server for Biology
    |May 20, 2024
    PubMed
    Summary

    P2Y1 receptor signaling exacerbates rotavirus infection, increasing diarrhea and viral shedding in mice. Blocking these receptors with MRS2500 reduced disease severity and transmission, indicating a potential therapeutic target.

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