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Two Difficult Pandemics: Tuberculosis and COVID-19
Zeynep Yegin Katran1, Aylin Babalık2, Ayla Türkar3
1Department of Allergy and Immunology, Süreyyapaşa Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
International Journal of Mycobacteriology
|May 21, 2024
Summary
Tuberculosis and COVID-19 coinfection (TB-COVID-19) involves two respiratory infections. This study found a low mortality rate and no significant aggravation between TB-COVID-19 cases.
Area of Science:
- Infectious Diseases
- Pulmonology
- Public Health
Background:
- Coinfection with Mycobacterium tuberculosis and SARS-CoV-2 presents as tuberculosis and COVID-19 coinfection (TB-COVID-19).
- Understanding the clinical, radiological, and laboratory features of TB-COVID-19 is crucial for effective management.
Purpose of the Study:
- To report the clinical, radiological, and laboratory findings.
- To describe the treatment processes for patients with TB-COVID-19 coinfection.
Main Methods:
- Retrospective analysis of patients aged 18+ hospitalized in the tuberculosis service from March 2020 to September 2022.
- Inclusion criteria: positive COVID-19 PCR during tuberculosis treatment or tuberculosis diagnosis during COVID-19 treatment.
Main Results:
- 39 patients (61.6% male, mean age 52) with TB-COVID-19 coinfection.
- 84.6% had pulmonary tuberculosis; 87.5% were sensitive to first-line drugs. Common symptoms: cough, sputum; lab: elevated C-reactive protein; CT: consolidation, tree-in-bud, cavitation.
- Low mortality rate (2.5%); neither disease aggravated the other's course.
Conclusions:
- TB-COVID-19 coinfection presents with significant respiratory symptoms.
- The study observed a low mortality rate and no mutual aggravation between tuberculosis and COVID-19.
- Findings highlight the importance of managing coinfections in respiratory diseases.
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