Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Action Potential01:31

Action Potential

7.9K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they...
7.9K
The Cochlea01:13

The Cochlea

44.8K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
44.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of the Hearing Benefits and User Satisfaction With Hearing Aids and Personal Sound Amplification Products: A Multicenter Prospective Randomized Crossover Trial.

Journal of Korean medical science·2026
Same author

A Position Statement on the Treatment of Hearing Impairment, Focused on Hearing Aids, From the Korean Otological Society Hearing Aid Study Group.

Journal of Korean medical science·2025
Same author

Over-the-Counter Hearing Aids Versus Traditional Hearing Aids in Patients With Mild-to-Moderate Hearing Loss: Protocol for a Noninferiority Randomized Controlled Trial.

JMIR research protocols·2024
Same author

Apple AirPods Pro as a Hearing Assistive Device in Patients with Mild to Moderate Hearing Loss.

Yonsei medical journal·2024
Same author

Clinical Portrait of Cochlear Implantation in Patients With CHARGE Syndrome.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2024
Same author

Cochlear implantation in patients with Charcot-Marie-Tooth disease: two cases with a review of the literature.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2024

Related Experiment Video

Updated: Jun 25, 2025

Performing Intracochlear Electrocochleography During Cochlear Implantation
09:10

Performing Intracochlear Electrocochleography During Cochlear Implantation

Published on: March 8, 2022

4.3K

Association Between Intracochlear Electrode Design and Electrically-Evoked Compound Action Potential Measures in

Jeong-Seo Kim1,2,3, Sung Hwa Hong1,4, Il Joon Moon1,5

  • 1Hearing Research Laboratory, Samsung Medical Center, Seoul, South Korea.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|May 22, 2024
PubMed
Summary

Cochlear implant electrode design impacts neural activation. Perimodiolar electrodes showed narrower spread of excitation and less channel interaction than lateral wall electrodes, potentially improving spectral resolution.

Keywords:
channel interactioncochlear implantelectrically‐evoked compound action potential (ECAP)intracochlear electrode arrayspread of excitation

More Related Videos

Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery
06:54

Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery

Published on: August 4, 2023

1.1K
Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

747

Related Experiment Videos

Last Updated: Jun 25, 2025

Performing Intracochlear Electrocochleography During Cochlear Implantation
09:10

Performing Intracochlear Electrocochleography During Cochlear Implantation

Published on: March 8, 2022

4.3K
Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery
06:54

Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery

Published on: August 4, 2023

1.1K
Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

747

Area of Science:

  • Audiology
  • Neurosurgery
  • Biomedical Engineering

Background:

  • Cochlear implant (CI) electrode designs have evolved, potentially affecting neural activation patterns.
  • Understanding the electrode-neuron interface is crucial for optimizing CI performance.

Purpose of the Study:

  • To evaluate the impact of different intracochlear electrode designs on neural activation spread and channel interaction.
  • To compare electrophysiological measures across various CI electrode configurations.

Main Methods:

  • A prospective cohort study involving 52 ears implanted with CIs.
  • Participants were grouped by electrode array design: lateral wall straight, slim perimodiolar, and old perimodiolar.
  • Electrically-evoked compound action potential (ECAP) metrics were used to assess spread of excitation (SOE) and channel interaction (CII).

Main Results:

  • No significant differences in ECAP threshold or slope were observed between groups.
  • Lateral wall straight electrodes exhibited significantly wider SOE half-widths and larger CII compared to perimodiolar electrodes.
  • Perimodiolar electrodes demonstrated significantly lower electrode impedance than lateral wall electrodes.

Conclusions:

  • Perimodiolar electrode designs resulted in narrower SOE half-widths and smaller CII, suggesting reduced neural overlap.
  • This electrode positioning may lead to improved spectral resolution in cochlear implant users.
  • The study highlights the importance of electrode design in modulating the electrode-neuron interface.