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Updated: Jun 25, 2025

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Synthesis, Isolation, and Reactivity Studies of 'Naked' Acyclic Gallyl and Indyl Anions
Debotra Sarkar1, Petra Vasko2, Tihomir Gluharev1
1Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, South Park Road, Oxford, OX1 3QR, UK.
Abstract:
By exploiting the electronic capabilities of the N-heterocyclic boryloxy (NHBO) ligand, we have synthesized "naked" acyclic gallyl [Ga{OB(NDippCH)2}2]- and indyl [In{OB(NDippCH)2}2]- anions (as their [K(2.2.2-crypt)]+ salts) through K+ abstraction from [KGa{OB(NDippCH)2}2] and [KIn{OB(NDippCH)2}2] using 2.2.2-crypt. These systems represent the first O-ligated gallyl/indyl systems, are ultimately accessed from cyclopentadienyl GaI/InI precursors by substitution chemistry, and display nucleophilic reactivity which is strongly influenced by the presence (or otherwise) of the K+ counterion.
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