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Updated: Jun 25, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[PET/CT in radiotherapy : indications and potential applications]
François Lucia1,2,3, Nadia Withofs3,4, Pierre Lovinfosse3,4
1Département de Radiothérapie-Oncologie, Hôpital Universitaire de Brest, France.
Functional imaging, such as positron emission tomography combined with computed tomography (PET/CT), aids radiotherapy by improving staging, patient selection, and treatment response assessment. This review explores its current integration and future potential in radiation oncology.
Area of Science:
- Oncology
- Radiotherapy
- Medical Imaging
Background:
- Functional imaging, including PET/CT, offers insights into biological properties relevant to cancer management.
- Current radiotherapy practices can benefit from advanced imaging techniques for improved patient outcomes.
Purpose of the Study:
- To review the current integration of functional imaging in radiotherapy.
- To explore the future potential contributions of functional imaging in radiation oncology.
Main Methods:
- Review of current literature on functional imaging in radiotherapy.
- Analysis of PET/CT applications in staging, treatment planning, and follow-up.
Main Results:
- Functional imaging enhances disease staging and patient selection for radiotherapy.
- PET/CT parameters can serve as predictive biomarkers for treatment response.
- Imaging aids in defining target volumes for dose escalation (dose-painting).
- Functional imaging is valuable for assessing treatment response during follow-up.
Conclusions:
- Functional imaging is integral to modern radiotherapy, impacting all stages of patient management.
- Future applications of functional imaging promise further optimization of radiotherapy delivery and patient care.
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