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Updated: Jun 25, 2025
Ex Vivo Corneal Organ Culture Model for Wound Healing Studies
Published on: February 15, 2019
Collagen-Based Artificial Cornea for Lamellar Keratoplasty: An Early Case Report
Andrey Yurevich Andreev1,2,3, Yusef Naim Yusef1, Sergey Eduardovich Avetisov1,2
1Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Purpose:
The aim of this study was to evaluate Viscoll collagen membrane (VCM) for lamellar keratoplasty.
Methods:
A 54-year-old man with grade 4 recurrent pterygium underwent lamellar keratoplasty using VCM as the graft material. Standard keratoplasty postoperative treatments, including topical antibiotic-corticosteroid and artificial tears, were administered.
Results:
Complete graft epithelialization was achieved after 4 days of the surgery. Follow-up at 9 months showed no pterygium recurrence as well as good integration of the VCM graft into the surrounding tissues with preserved transparency.
Conclusions:
This case demonstrated that VCM possesses great potential as an alternative to the human donor cornea for lamellar keratoplasty; however, the application of VCM for lamellar keratoplasty still needs additional evaluation.
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