Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

2.1K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.1K
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

301
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
301
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

169
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
169
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

3.1K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
3.1K
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

45.9K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of Hypertensive Disorders of Pregnancy and Associated Birth Outcomes Among Adolescent Mothers at a Tertiary Hospital in Zambia: A Retrospective Cross-Sectional Study.

International journal of hypertension·2026
Same author

Mechanisms and integrative machine learning approaches to blood-brain barrier biomarker profiling for personalized ischemic stroke management.

Physiological reports·2026
Same author

Junctophilin-2-orchestrated calcium signalosome regulates brown adipocyte thermogenesis and energy metabolism.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Annexin A6 Modulates the Secretion of Pro-Inflammatory Cytokines and Exosomes via Interaction with SNAP23 in Triple-Negative Breast Cancer Cells.

Cells·2026
Same author

Monocyte Oxidative Stress Underlies Persistent Immune Activation in Long COVID Postural Orthostatic Tachycardia Syndrome.

medRxiv : the preprint server for health sciences·2026
Same author

Aging Remodels Mitochondrial Architecture Across the Male Reproductive Axis.

Research square·2026

Related Experiment Video

Updated: Jun 25, 2025

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.5K

HIV-Associated Hypertension: Risks, Mechanisms, and Knowledge Gaps.

Prem Prakash1,2,3, Berwin Singh Swami Vetha4, Rajasree Chakraborty1,2,3

  • 1The Center for AIDS Health Disparities Research (P.P., R.C., G.M., M.B., C.D.), Meharry Medical College, Nashville, TN.

Circulation Research
|May 23, 2024
PubMed
Summary

HIV-1 infection, while manageable with antiviral therapy, increases the risk of cardiovascular issues like hypertension. Further research is needed to understand and address these non-AIDS-related comorbidities in people living with HIV.

Keywords:
cardiovascular diseasescytopathogenic effect, viralnoncommunicable diseasesquality of lifesodium chloride, dietary

More Related Videos

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
06:07

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Published on: October 6, 2022

2.4K
Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

719

Related Experiment Videos

Last Updated: Jun 25, 2025

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.5K
Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
06:07

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Published on: October 6, 2022

2.4K
Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

719

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Immunology

Background:

  • HIV-1 infection leads to immune decline and AIDS, causing millions of deaths.
  • Antiviral therapy controls HIV-1, transforming it into a chronic condition but not a cure.
  • Increased lifespan in people with HIV results in non-AIDS-related morbidities, including cardiovascular diseases.

Purpose of the Study:

  • To review the current knowledge on cardiovascular comorbidities in HIV-1 infection.
  • To focus on hypertension as a key comorbidity associated with HIV-1.
  • To discuss potential mechanisms and knowledge gaps in HIV-1-associated hypertension.

Main Methods:

  • Literature review of current research on HIV-1 and cardiovascular comorbidities.
  • Analysis of mechanisms contributing to HIV-1-associated hypertension.
  • Identification of research gaps and future directions.

Main Results:

  • HIV-1 infection is linked to various cardiovascular diseases.
  • Hypertension is a significant comorbidity in people living with HIV.
  • Several potential mechanisms drive HIV-1-associated hypertension, but understanding is incomplete.

Conclusions:

  • HIV-1-associated hypertension is a growing concern in the post-antiviral therapy era.
  • Further research is crucial to elucidate the underlying factors and pathways of HIV-1-associated hypertension.
  • Addressing these comorbidities is essential for improving long-term health outcomes in people with HIV.