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Anonymizing medical case-based explanations through disentanglement.

Helena Montenegro1, Jaime S Cardoso1

  • 1Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias s/n, 4200-465 Porto, Portugal; INESC TEC, Rua Dr. Roberto Frias s/n, 4200-465 Porto, Portugal.

Medical Image Analysis
|May 23, 2024
PubMed
Summary

This study introduces a new method to anonymize medical images by disentangling identity and medical features, enabling privacy-preserving case-based explanations for deep learning models in healthcare.

Keywords:
Case-based explanationsDeep generative modelsDisentangled representation learningImage anonymizationMedical image generationPrivacy

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Area of Science:

  • Artificial Intelligence
  • Medical Imaging
  • Computer Vision

Background:

  • Deep learning models offer valuable insights into clinical decision-making through case-based explanations.
  • Sharing medical images for these explanations raises significant patient privacy concerns.
  • Existing anonymization methods may compromise the integrity of medical information.

Purpose of the Study:

  • To develop a novel method for disentangling identity and medical characteristics in images.
  • To anonymize medical images while preserving their diagnostic content for privacy-preserving explanations.
  • To enable the generation of realistic synthetic identities for anonymized medical data.

Main Methods:

  • A disentanglement mechanism was designed to separate identity and medical feature vectors within images.
  • A model was developed to generate synthetic, privacy-preserving identities to replace original image identities.
  • The proposed models were applied to both medical and biometric datasets for validation.

Main Results:

  • The method successfully anonymized medical images, generating realistic outputs that retained original medical information.
  • The disentanglement process effectively separated identity from medical characteristics.
  • The models demonstrated the ability to generate counterfactual images by altering medical features.

Conclusions:

  • The proposed approach effectively anonymizes medical images, addressing privacy concerns in AI-driven clinical decision support.
  • This technique facilitates the use of case-based explanations with sensitive medical data.
  • The method holds potential for generating synthetic medical data and exploring counterfactual scenarios.