Related Experiment Video
Updated: Jun 25, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Hypoxaemia risk in pediatric flexible bronchoscopy for foreign body removal: a retrospective study
Su-Jing Zhang1,2, Min-Yi Lin1, Min Zhou1,2
1College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Department of Anesthesiology, Fujian Children's Hospital(Fujian Branch of Shanghai Children's Medical Center), Fujian Key Laboratory of Women and Children's Critical Diseases ReseFujian Medical Universityarch, Fuzhou, China.
Insights
Hypoxemia is common during pediatric foreign body (FB) removal via bronchoscopy. Longer operation times, larger FBs, and pneumonia increase this risk.
Area of Science:
- Pediatric Pulmonology
- Anesthesiology
- Medical Device Safety
Background:
- Hypoxemia is the most frequent adverse event during pediatric flexible bronchoscopy for foreign body (FB) removal.
- Untreated hypoxemia can lead to cardiac or respiratory arrest.
- Risk factors for hypoxemia during FB removal require further definition.
Purpose of the Study:
- To identify specific risk factors associated with hypoxemia during flexible bronchoscopy for foreign body retrieval in pediatric patients.
- To inform clinical practice and improve patient safety during these procedures.
Main Methods:
- Retrospective analysis of 266 pediatric patients undergoing flexible bronchoscopy for FB extraction between January 1, 2015, and December 31, 2022.
- Utilized supraglottic airway for anesthesia apparatus connection during procedures.
- Employed multivariate analysis to determine significant risk factors for hypoxemia.
Main Results:
- Hypoxemia occurred in 16.9% (45/266) of pediatric patients.
- Significant risk factors for hypoxemia included: operation time >60 minutes (OR 8.55), maximum FB diameter >7 mm (OR 5.03), and pneumonia on imaging (OR 2.69).
- These factors were identified through multivariate analysis with associated confidence intervals.
Conclusions:
- Pediatric patients undergoing flexible bronchoscopy for FB removal are susceptible to hypoxemia.
- Extended procedure duration, larger foreign body size, and presence of pneumonia are significant predictors of increased hypoxemia risk.
- Identifying these risk factors can guide preventative strategies and management during bronchoscopy.
Background:
Hypoxemia represents the most prevalent adverse event during flexible bronchoscopy procedures aimed at foreign body retrieval in pediatric patients; if not expeditiously managed, it carries the potential for cardiac or respiratory arrest. The specific risk factors contributing to the occurrence of hypoxemia during foreign body FB removal via bronchoscopy have yet to be definitively established.
Methods:
This retrospective study included a cohort of 266 pediatric subjects from January 1, 2015, to December 31, 2022, who underwent flexible bronchoscopy for the purpose of FB extraction. In this cohort, the supraglottic airway was used to connect the anesthesia apparatus during the removal procedure.
Results:
In total, 45 of the pediatric patients (16.9%) experienced episodes of hypoxemia during the FB removal procedure. Multivariate analysis revealed that the following factors were significantly associated with the occurrence of hypoxemia: an operation time exceeding 60 min (odds ratio [OR] 8.55; 95% confidence interval [CI] 3.82-19.13), a maximum diameter exceeding 7 mm (OR 5.03; 95% CI, 2.24-11.29), and the presence of radiological evidence indicating pneumonia (OR 2.69; 95% CI, 1.27-5.69).
Conclusion:
During flexible bronchoscopy procedures aimed at FB removal in pediatric patients, there is an increased susceptibility to hypoxemia. Factors including extended operation duration, larger FB dimensions, and radiographic evidence suggestive of pneumonia significantly contribute to a heightened risk of hypoxemia.
Related Concept Videos
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

