Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conductive and piezoelectric biomaterials: a comprehensive review of load-bearing soft tissue repair.

Biomaterials science·2025
Same author

Neuroprotective and Anti-inflammatory Dual-Phenotypic Drug Screening Strategies.

ACS chemical neuroscience·2025
Same author

Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.

Genome medicine·2025
Same author

Rapid and efficient nitrogen removal by a novel heterotrophic nitrification-aerobic denitrification bacteria Marinobacterium maritimum 5-JS in aquaculture wastewater: Performance and potential applications.

Environmental research·2025
Same author

Improvement in multiple cognitive domains via combined revascularization by 6 months' follow-up: a new potential surgical indication in moyamoya disease.

Journal of neurosurgery·2025
Same author

A Spatiotemporal Analysis of a High-Resolution Molecular Network Reveals Shifts of HIV-1 Transmission Hotspots in Guangzhou, China.

Viruses·2025
Same journal

Multiphysics Investigation on Thermal Characteristics of Internal Bio-Inspired V-Ribbed Cooling Channels for Outer Rotor PMSM.

Biomimetics (Basel, Switzerland)·2026
Same journal

Smart Logistics Model for Supply Chain Management via Brain-Inspired Geometric Deep Networks.

Biomimetics (Basel, Switzerland)·2026
Same journal

A Systematic Taxonomy of the Sunflower Optimization Algorithm: Variants, Hybridization Strategies, Applications, and Research Directions.

Biomimetics (Basel, Switzerland)·2026
Same journal

Toward a Compositional Theory of Trust in Embodied Intelligence: A QNLP Framework for Modeling Context, Interaction, and Trustworthiness.

Biomimetics (Basel, Switzerland)·2026
Same journal

Empirical Logic for Bio-Inspired Soft Computing: Illustrative Applications in Control Engineering and Cluster Analysis.

Biomimetics (Basel, Switzerland)·2026
Same journal

A Modified Multi-Strategy Dhole Optimization Algorithm and Its Engineering Applications.

Biomimetics (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: May 12, 2026

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K

A Microactuator Array Based on Ionic Electroactive Artificial Muscles for Cell Mechanical Stimulation.

Jing Gu1, Zixing Zhou1, Yang Xie1

  • 1Department of Engineering Mechanics, School of Civil Engineering, Wuhan University, Wuhan 430072, China.

Biomimetics (Basel, Switzerland)
|May 24, 2024
PubMed
Summary
This summary is machine-generated.

Researchers developed an electroactive polymer (EAP) microactuator array for precise cell mechanical stimulation. This innovation advances in vitro biomechanics research and biomimetic device design.

Keywords:
artificial musclebiomechanicselectro-actuationelectroactive polymermicroactuator

More Related Videos

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential
07:41

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

7.5K
Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

8.3K

Related Experiment Videos

Last Updated: May 12, 2026

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1
11:22

Cardiac Muscle-cell Based Actuator and Self-stabilizing Biorobot - PART 1

Published on: July 11, 2017

8.1K
Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential
07:41

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

7.5K
Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators
14:42

Fabrication of Carbon-Based Ionic Electromechanically Active Soft Actuators

Published on: April 25, 2020

8.3K

Area of Science:

  • Biomechanics
  • Biomaterials Science
  • Cellular Mechanobiology

Background:

  • Mechanical stimulation is crucial for cellular functions, driving interest in in vitro simulation techniques.
  • Ionic electroactive polymers (EAPs) show potential as artificial muscles for biomechanical applications.
  • Existing methods for cell mechanical stimulation using EAPs require further development for practical use.

Purpose of the Study:

  • To develop and evaluate a microactuator array using ionic EAP artificial muscles for precise cell mechanical stimulation.
  • To demonstrate the feasibility of using laser cutting for fabricating EAP microactuator arrays.
  • To assess the electro-actuation performance of the developed microactuators for potential biomechanical applications.

Main Methods:

  • Fabrication of a 5x5 microactuator array on a supporting membrane using laser cutting.
  • Experimental testing to evaluate the electro-actuation performance of individual microactuators.
  • Numerical simulations to complement experimental data and validate performance.

Main Results:

  • Successful fabrication of an ionic EAP microactuator array.
  • Experimental validation of the electro-actuation performance of the microactuators.
  • Numerical simulations confirmed the potential for controlled mechanical stimulation of cells.

Conclusions:

  • The developed ionic EAP microactuator array shows promise for advanced cell mechanical stimulation in vitro.
  • The fabrication approach offers a pathway for creating miniaturized intelligent electronic devices.
  • This work contributes to the fields of biomechanics, biomimetics, and microelectronic device innovation.