Related Experiment Video
Updated: May 6, 2026
07:56
Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
Published on: November 16, 2018
6.8K
Leveraging Dental Stem Cells for Oral Health during Pregnancy: A Concise Review
Aida Meto1,2,3, Ana Sula4, Samuele Peppoloni2
1Department of Dentistry, Faculty of Dental Sciences, University of Aldent, 1007 Tirana, Albania.
Dentistry Journal
|May 24, 2024
Summary
Dental stem cells (DSCs) show promise for improving oral health during pregnancy. This review examines their potential applications, safety, and ethical considerations for maternal dental care.
Area of Science:
- Oral Health
- Regenerative Medicine
- Maternal Health
Background:
- Pregnancy involves hormonal shifts impacting oral health, necessitating preventive dental care.
- Dental stem cells (DSCs) from dental pulp and periodontal ligaments are key in regenerative dentistry.
- Current DSC applications are widespread, but use during pregnancy needs careful evaluation.
Purpose of the Study:
- To review advancements, challenges, and future prospects of using DSCs for oral health issues in pregnant women.
- To explore the potential of DSCs in preventive and regenerative dental therapies during pregnancy.
- To provide a comprehensive understanding of DSC applications for improving maternal oral health.
Main Methods:
- Literature review of recent advancements in DSC research.
- Analysis of safety, ethical considerations, and regulatory aspects of DSC use in pregnant women.
- Exploration of interdisciplinary collaboration needs for DSC implementation.
Main Results:
- DSCs present promising regenerative and preventive potential for pregnancy-related oral health concerns.
- Key considerations include safety, ethical implications, and regulatory frameworks for DSC use in pregnant individuals.
- Interdisciplinary collaboration is vital for responsible and effective implementation.
Conclusions:
- DSCs offer a novel approach to enhance maternal oral health during pregnancy.
- Careful consideration of safety, ethics, and regulations is paramount for DSC application in pregnant women.
- Further research and collaboration are needed to fully realize the potential of DSCs in this population.
Related Concept Videos
01:19Mesenchymal Stem Cells
4.5K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
4.5K
01:10Zygotic Development And Stem Cell Formation
6.4K
The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
6.4K
01:27Source And Potency Of Stem Cells
5.0K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
5.0K
01:17Stem Cell Culture
4.6K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
4.6K
01:15Teeth
2.2K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.2K
01:28Development of the Oral Microbiota
75
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
75