Related Experiment Video
Updated: May 8, 2026
09:44
Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
16.1K
Probiotic Effect of Streptococcus dentisani on Oral Pathogens: An In Vitro Study.
Claudia María Bedoya-Correa1, Santiago Betancur-Giraldo2, John Franco1,3
1GIOM Group, Faculty of Dentistry, Universidad Cooperativa de Colombia, Medellin 055421, Colombia.
Pathogens (Basel, Switzerland)
|May 24, 2024
Summary
Streptococcus dentisani shows probiotic potential by reducing pathogenic biofilms like Streptococcus mutans and Candida albicans. This oral probiotic effectively inhibits biofilm formation through displacement and competition strategies.
Area of Science:
- Microbiology
- Oral Health
- Probiotics
Background:
- Probiotics are explored to restore oral microbial balance and prevent pathogenic biofilm development.
- Streptococcus dentisani is investigated for its potential role in oral health.
Purpose of the Study:
- To evaluate the probiotic capacity of Streptococcus dentisani against biofilms of Streptococcus mutans, Streptococcus mitis, and Candida albicans.
- To determine the effectiveness of S. dentisani using competition, exclusion, and displacement strategies in inhibiting biofilm formation.
Main Methods:
- Assessing monospecies biofilm formation by all tested strains.
- Evaluating the probiotic potential of S. dentisani against S. mutans, S. mitis, and C. albicans biofilms using in vitro competition, exclusion, and displacement assays.
Main Results:
- S. dentisani demonstrated moderate biofilm production.
- While competition and exclusion effects were not significant against S. mutans and S. mitis, S. dentisani significantly reduced pathogenic streptococcal biofilms via displacement.
- S. dentisani notably inhibited C. albicans biofilm formation through competition and displacement.
Conclusions:
- In vitro, S. dentisani exhibits probiotic properties beneficial for reducing potentially pathogenic biofilms.
- Further research is needed to elucidate the specific mechanisms by which S. dentisani inhibits biofilm formation.
Related Concept Videos
01:22Probiotics
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
01:27The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...