Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diversity in Cell Signaling Responses

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity.
Graded and Abrupt Responses
Some signaling systems generate...

Stress Response System

Stress Response System

The stress response system, also known as the fight-or-flight response, is the body's automatic physiological reaction to perceived threats. Hans Selye introduced the concept of General Adaptation Syndrome (GAS) to describe the predictable pattern of changes that occur in response to stress. GAS consists of three sequential stages: alarm, resistance, and exhaustion. This model helps explain how chronic stress can contribute to health problems.
Alarm stage
In the alarm stage, the body's...

Protein Dynamics in Living Cells

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Interventions to improve timely cancer diagnosis: an integrative review.

Diagnosis (Berlin, Germany)·2024

Same author

Pulse Oximetry Con: Stop Living in the Cave.

Critical care medicine·2023

Same author

SWIFT: A deep learning approach to prediction of hypoxemic events in critically-Ill patients using SpO2 waveform prediction.

PLoS computational biology·2021

Same author

Safety Culture as a Patient Safety Practice for Alarm Fatigue.

JAMA·2021

Same author

SWIFT: A Deep Learning Approach to Prediction of Hypoxemic Events in Critically-Ill Patients Using SpO <sub>2</sub> Waveform Prediction.

medRxiv : the preprint server for health sciences·2021

Same author

Management of Coronavirus Disease 2019 Intubation Teams.

A&A practice·2020

Same journal

Critical Care and Contagion: Evolving Frontiers of Infectious Diseases in the Modern Intensive Care Unit.

Critical care clinics·2026

Same journal

Advances and Challenges in Sepsis Care in Low-Resource Settings.

Critical care clinics·2026

Same journal

The Respiratory Triple Pandemic in the Intensive Care Unit: Epidemiology, Clinical Features and Management of COVID-19, Influenza and Respiratory Syncytial Virus.

Critical care clinics·2026

Same journal

Antibiotic Stewardship for the Intensivist.

Critical care clinics·2026

Same journal

Infection Prevention and Control in the Intensive Care Unit.

Critical care clinics·2026

Same journal

Antibiotic Considerations in the Critically Ill: Empiric Choices and Dosing.

Critical care clinics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 25, 2025

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Published on: March 17, 2019

Rapid Response Systems.

Bradford D Winters¹

¹Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 9127 Zayed 1800 Orealns Street, Baltimore, MD 21287, USA.

Critical Care Clinics

|May 25, 2024

Summary

This summary is machine-generated.

Hospital rapid response systems (RRS) prevent patient deaths and cardiopulmonary arrests on general wards. Enhancing these systems further improves patient safety and reduces mortality.

Keywords:

Cardiopulmonary arrest Clinical deterioration Mortality Rapid response systems

More Related Videos

Using Rapid Serial Visual Presentation to Measure Set-Specific Capture, a Consequence of Distraction While Multitasking

Using Rapid Serial Visual Presentation to Measure Set-Specific Capture, a Consequence of Distraction While Multitasking

Published on: August 29, 2018

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

Published on: August 25, 2020

Related Experiment Videos

Last Updated: Jun 25, 2025

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Published on: March 17, 2019

Using Rapid Serial Visual Presentation to Measure Set-Specific Capture, a Consequence of Distraction While Multitasking

Using Rapid Serial Visual Presentation to Measure Set-Specific Capture, a Consequence of Distraction While Multitasking

Published on: August 29, 2018

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles

Published on: August 25, 2020

Area of Science:

Medical Science
Patient Safety
Healthcare Quality Improvement

Background:

The hospital rapid response system (RRS) is a key component of the "ICU without walls" model.
RRSs are designed to address clinical deterioration on general hospital wards.
Existing RRSs have demonstrated effectiveness in preventing cardiopulmonary arrests and reducing hospital mortality.

Purpose of the Study:

To evaluate the impact of targeted improvements on existing RRS effectiveness.
To explore methods for enhancing the benefits of RRS interventions.
To further optimize patient safety and reduce mortality through RRS modifications.

Main Methods:

Analysis of data from existing RRS implementations.
Identification of specific areas for targeted improvements within RRS protocols.
Implementation and evaluation of modified RRS strategies.

Main Results:

Demonstrated enhancement of RRS benefits through specific modifications.
Evidence of improved patient outcomes with targeted RRS enhancements.
Quantified reduction in adverse events and mortality following RRS improvements.

Conclusions:

Targeted improvements can significantly enhance the effectiveness of hospital rapid response systems.
Optimizing RRS interventions leads to better patient safety and reduced mortality.
Further research into RRS modifications is warranted to maximize patient care.