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Related Experiment Video

Updated: Jun 25, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Oral Psoriasis Therapies.

JaBreia James¹, Tracey Otto², Julia Gao²

¹Harvard Combined Dermatology Residency Program, Department of Dermatology, Harvard Medical School, 55 Fruit Street, BH 616 Boston, MA 02114, USA.

Dermatologic Clinics

|May 25, 2024

Summary

Oral psoriasis treatments offer effective options, including traditional immunosuppressants and newer targeted agents. Patients may prefer these oral medications over injections for managing psoriasis.

Keywords:

Acitretin Baricitinib Cyclosporine Jak inhibitors Methothrexate Psoriasis Psoriatic arthritis Tofacitinib

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Last Updated: Jun 25, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Published on: October 27, 2023

Area of Science:

Dermatology
Pharmacology

Background:

Psoriasis is a chronic inflammatory skin condition with various treatment options.
Oral therapies are a key component in managing psoriasis, offering an alternative to injectable medications.

Purpose of the Study:

To review existing and emerging oral agents for psoriasis treatment.
To discuss the role of these oral therapies in the current treatment landscape.

Main Methods:

Literature review of traditional and novel oral psoriasis medications.
Analysis of the efficacy and administration route preferences for oral psoriasis therapies.

Main Results:

Traditional oral immunosuppressants (methotrexate, cyclosporine, acitretin) are effective.
Newer targeted oral agents (apremilast, deucravacitinib, IL-23 receptor antagonists) provide advanced treatment options.

Conclusions:

Both older and newer oral psoriasis therapies are valuable tools.
Oral administration is a preferred route for many patients, influencing treatment choices.