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Optimizing the Antimicrobial Effects by using Natural Compounds in COVID-19 Management
Amin Gasmi1, Asma Gasmi Benahmed2, Maryam Dadar3
1Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.
Current Medicinal Chemistry
|May 27, 2024
Summary
Combining natural compounds with existing antibiotics and antivirals shows promise for combating drug-resistant bacteria and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This approach enhances antimicrobial potential and may reduce side effects, offering a new strategy against COVID-19 and antimicrobial resistance.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes significant global health issues, leading to lung damage and death.
- COVID-19 patients are susceptible to secondary infections by multidrug-resistant respiratory pathogens like Pseudomonas aeruginosa and Staphylococcus aureus.
- Existing antibiotics are often ineffective against these resistant bacteria, necessitating novel therapeutic strategies.
Purpose of the Study:
- To review studies combining natural compounds with antibiotics and antivirals.
- To explore strategies for enhancing the efficacy of antimicrobial agents against COVID-19 and resistant pathogens.
- To provide a foundation for developing new antimicrobial agents.
Main Methods:
- Literature review of studies investigating the synergistic effects of natural compounds and antimicrobial drugs.
- Analysis of data on enhanced antimicrobial activity and potential reduction in side effects.
- Synthesis of existing research to identify promising therapeutic avenues.
Main Results:
- Natural compounds can increase the antimicrobial activity of existing antibiotics and antivirals.
- Combinatorial approaches show potential in combating multidrug-resistant infections.
- Natural compounds may offer a safer alternative or adjunct therapy, potentially reducing drug side effects.
Conclusions:
- Combining natural compounds with conventional antimicrobial agents is a promising strategy against COVID-19 and antimicrobial resistance.
- Further research is needed to develop novel antimicrobial agents based on these synergistic combinations.
- This approach holds potential for creating more effective and safer treatments for infectious diseases.
Keywords:
COVID-19antibioticsantimicrobial resistancenatural compoundsrespiratory pathogenstherapeutic agents.More Related Videos
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