Related Experiment Video
Updated: Jun 25, 2025

12:38
Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies
Published on: July 19, 2007
6.2K
'Science by consensus' impedes scientific creativity and progress: A simple alternative to funding biomedical
1Department of Biomedical Sciences, University of the Pacific - San Francisco Campus, San Francisco, CA, 94103, USA.
F1000Research
|May 27, 2024
Summary
Low success rates in grant applications hinder scientific progress. This study critiques the National Institutes of Health (NIH) and National Science Foundation (NSF) peer review process, proposing a more equitable funding alternative.
Area of Science:
- Scientific funding and policy
- Research evaluation methodologies
Background:
- Grant application success rates at NIH and NSF are critically low, impeding scientific advancement and researchers' careers.
- The current peer review system for grant proposals is widely accepted but lacks scientific validation against alternatives.
Purpose of the Study:
- To identify and detail major problems within the existing scientific peer review process.
- To propose and advocate for a scientifically evaluated, equitable alternative funding system.
Main Methods:
- Delineation of 15 significant issues inherent in the current peer review system.
- Proposal of a novel funding model that bypasses traditional peer review.
Main Results:
- The proposed alternative system aims to fund significantly more principal investigators, including early-career scientists, with reduced overall budget.
- Elimination of the peer review stage is central to the proposed system's efficiency and cost-effectiveness.
Conclusions:
- The current peer review system for grant applications is scientifically unevaluated and detrimental.
- Implementation of an alternative, equitable funding model is necessary to foster scientific progress and support a broader range of researchers.
Related Concept Videos
Synthetic Biology
4.7K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
4.7K
The Fossil Record
25.1K
The fossil record documents only a small fraction of all organisms that have ever inhabited Earth. Fossilization is a rare process, and most organisms never become fossils. Moreover, the fossil record only exhibits fossils that have been discovered. Nevertheless, sedimentary rock fossils of long-lived, abundant, hard-bodied organisms dominate the fossil record. These fossils offer valuable information, such as an organism's physical form, behavior, and age. Studying the fossil record helps...
25.1K
Biodiversity and Human Values
13.0K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
13.0K
EPS and iPS Cells in Disease Research
2.8K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
2.8K
Ethics in Research
23.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.0K
The Evidence for Evolution
42.7K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
42.7K

