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Updated: Jun 25, 2025
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Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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Topical Atropine for Myopia Control: A Review
1Medical Center, Eye Center, University Freiburg, Germany.
Klinische Monatsblatter Fur Augenheilkunde
|May 27, 2024
Summary
Topical atropine effectively prevents myopia in children, with efficacy and side effects depending on dosage. New research examines its use in diverse populations and primary prevention strategies.
Area of Science:
- Ophthalmology
- Pediatric eye care
- Myopia control
Background:
- Atropine eye drops are a proven intervention for slowing myopia progression in children.
- Previous research, primarily from Asian populations, established atropine's safety and efficacy.
- A dose-dependent relationship exists between atropine concentration and both therapeutic effects and adverse events.
Purpose of the Study:
- To review recent data on atropine for myopia control in predominantly white populations.
- To investigate potential ethnicity-dependent variations in atropine's efficacy and side effect profile.
- To explore the role of atropine in the primary prevention of new-onset myopia.
Main Methods:
- Systematic review of recent clinical trials and observational studies.
- Analysis of data stratified by ethnicity and atropine dosage.
- Evaluation of studies focusing on incident myopia prevention.
Main Results:
- Efficacy and tolerability of atropine vary across different ethnic groups.
- Lower atropine concentrations may offer a favorable balance between efficacy and side effects.
- Evidence suggests potential for atropine in preventing myopia onset, not just progression.
Conclusions:
- Atropine remains a key strategy for pediatric myopia management.
- Further research is needed to optimize atropine use across diverse populations.
- Personalized approaches considering ethnicity and dosage are crucial for effective myopia prevention.
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