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Neutral rhodol-based dyes expressing localization in mitochondria
Ilaria Ferraboschi1, Juraj Ovčar2,3, Kateryna V Vygranenko4
1Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy. cristina.sissa@unipr.it.
Organic & Biomolecular Chemistry
|May 28, 2024
Abstract:
Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies. A simple model is proposed to explain the localization mechanism of neutral molecules. The model takes into account the strong coupling between the molecular dipole moment and the electric field of the inner mitochondrial membrane.

