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Respiratory Viral Coinfections in Pediatric Patients in the Primary Care Setting: A Multicenter Prospective Study

Cristina Andrés1, Aida Perramon-Malavez2, Anna Creus-Costa3,4

  • 1Respiratory Virus Unit, Microbiology Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus.

The Journal of Infectious Diseases
|May 28, 2024
PubMed

Insights

This study tracked pediatric respiratory viruses for two years. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coinfection was common, often with rhinovirus or influenza A, impacting public health strategies.

Area of Science:

  • Pediatric infectious diseases
  • Virology
  • Epidemiology

Background:

  • Acute respiratory viral infections represent a substantial global health challenge for children.
  • Limited data exist on viral dissemination patterns in communities during the COVID-19 pandemic.

Purpose of the Study:

  • To investigate the prevalence and coinfection dynamics of respiratory viruses in pediatric primary care patients.
  • To understand viral interactions in the post-COVID-19 pandemic era.

Main Methods:

  • A 2-year prospective, multicenter study involving 1276 pediatric patients in Catalonia, Spain.
  • Analysis of coinfection rates among various respiratory viruses.
  • Data collected from primary care settings.

Main Results:

  • A significant coinfection rate of 23.8% was observed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
  • SARS-CoV-2 frequently coinfected with rhinovirus or influenza A.
  • Complex patterns of viral coinfection were identified.

Conclusions:

  • The findings offer crucial insights into post-pandemic viral interactions in children.
  • Understanding these dynamics is essential for effective public health interventions and management of pediatric respiratory illnesses.

Keywords:
RSVSARS-CoV-2childrencoinfectionsprimary care

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