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Essential voice tremor: treatment with propranolol
Neurology
|January 1, 1985
Summary
Chronic oral propranolol did not improve voice tremor or quality in patients with essential voice tremor. However, it significantly reduced hand tremor amplitude, suggesting voice tremor is more resistant to this therapy.
Area of Science:
- Neurology
- Pharmacology
Background:
- Essential voice tremor is a neurological condition affecting vocal cord function.
- Oral propranolol is a beta-blocker medication sometimes used to manage tremors.
Purpose of the Study:
- To evaluate the efficacy of chronic oral propranolol in treating essential voice tremor.
- To compare the effects of propranolol and placebo on voice tremor and quality.
Main Methods:
- A randomized, placebo-controlled study involving seven patients with essential voice tremor.
- Patients received either chronic oral propranolol or a placebo.
- Assessment of voice tremor and voice quality scores.
Main Results:
- No significant difference in voice tremor or voice quality scores between the propranolol and placebo groups.
- A significant reduction in hand tremor amplitude was observed with propranolol therapy.
- Voice tremor demonstrated greater resistance to propranolol compared to hand tremor.
Conclusions:
- Chronic oral propranolol therapy is not effective in improving voice tremor or quality in patients with essential voice tremor.
- Propranolol shows efficacy in reducing hand tremor amplitude but not voice tremor.
- Further research is needed to explore alternative treatments for essential voice tremor.