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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Recent Advancement of Nanotheranostics in Cancer Applications.

Suphiya Parveen1, R Abira1, Safal Paikray2

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Nanotheranostics combines disease detection and treatment using nanoparticles for real-time monitoring. This approach enhances cancer prognosis and therapy evaluation through advanced nanomaterials.

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Area of Science:

  • Nanomedicine
  • Biomaterials Science
  • Medical Imaging

Background:

  • Nanotheranostics integrates diagnostic and therapeutic agents on a single platform.
  • This approach enables simultaneous disease detection, treatment, and real-time monitoring of drug delivery and efficacy.
  • Cancer theranostics offers a safer and more effective approach to improving patient prognosis.

Purpose of the Study:

  • To review various nanoparticles and nanomaterials utilized in theranostic applications.
  • To highlight the potential of nanotheranostics in disease detection and treatment.
  • To discuss the role of nanotheranostics in advancing precision medicine.

Main Methods:

  • Review of current literature on nanomedicine and theranostic applications.
  • Discussion of different classes of nanomaterials, including magnetic nanoparticles, quantum dots, upconversion nanoparticles, mesoporous silica nanoparticles, carbon-based nanoparticles, and organic dye-based nanoparticles.
  • Exploration of the integration of these nanomaterials with imaging modalities like MRI, PET, and SPECT.

Main Results:

  • Various nanoscale biomaterials demonstrate significant potential for theranostic activity.
  • Nanotheranostic agents can be developed for multifunctional applications in advanced imaging systems.
  • The review categorizes and discusses diverse nanomaterials employed in theranostics.

Conclusions:

  • Nanotheranostics holds immense promise for simultaneous disease diagnosis and therapy.
  • The development of clinically translatable nanomaterials is crucial for future theranostic research.
  • Continued research in nanotheranostics is expected to drive advancements in disease detection and chemotherapeutic treatments.