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Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

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Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
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Guest Editorial: Implantable bioelectronics.

Yael Hanein1, Josef Goding2

  • 1School of Electrical Engineering, Tel Aviv University, Tel Aviv, Israel.

APL Bioengineering
|May 30, 2024
PubMed
Summary
This summary is machine-generated.

Implantable bioelectronics merge technology and medicine to create devices that restore or monitor bodily functions, improving patient lives. Advances in materials and miniaturization drive innovation, though challenges remain in areas like vision restoration.

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Area of Science:

  • Implantable bioelectronics represents a multidisciplinary frontier in medical science.
  • It integrates engineering, biology, and medicine for therapeutic and monitoring applications.

Background:

  • Established devices include cochlear implants, pacemakers, deep brain stimulators, and vagus nerve stimulators.
  • These technologies address diverse conditions such as hearing loss, cardiac arrhythmias, and neurological disorders.

Discussion:

  • Recent advancements in materials science, nanotechnology, and microfabrication are enabling more sophisticated, smaller, and biocompatible devices.
  • Challenges persist, particularly in enhancing the efficacy of devices like retinal prostheses for vision restoration.

Key Insights:

  • Implantable bioelectronic devices offer significant potential to improve patient outcomes and quality of life.
  • The field is crucial for addressing the health needs of an aging population with increasing chronic diseases.

Outlook:

  • The convergence of societal health demands, technological progress, and innovation support positions bioelectronics at a pivotal research stage.
  • Continued development promises enhanced treatments for a wide range of medical conditions.