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An evaluation of the TCu 380Ag and the Multiload Cu375
Fertility and Sterility
|February 1, 1985
Summary
Two copper intrauterine devices, TCu 380Ag and Multiload Cu375, demonstrated similar low pregnancy and high continuation rates in a clinical trial. These findings suggest both intrauterine devices (IUDs) are safe and effective for long-term contraception.
Area of Science:
- Reproductive Medicine
- Medical Device Evaluation
- Contraception
Background:
- Intrauterine devices (IUDs) are a common form of reversible contraception.
- Evaluating the safety and efficacy of different IUD models is crucial for clinical practice.
Purpose of the Study:
- To compare the performance of the TCu 380Ag and Multiload Cu375 intrauterine devices.
- To assess pregnancy, continuation, and complication rates associated with these IUDs.
Main Methods:
- A multicenter clinical trial involving 1477 women.
- Life-table analysis was used to evaluate cumulative event rates.
Main Results:
- Both TCu 380Ag and Multiload Cu375 IUDs exhibited similar, low event rates.
- Cumulative pregnancy rates were below 1.0% at one year.
- Continuation rates were approximately 90% at one year.
- The risk of hospitalization or pelvic infection was low for both devices.
Conclusions:
- The TCu 380Ag and Multiload Cu375 intrauterine devices are safe and effective contraceptive options.
- Both IUDs offer high continuation rates and low pregnancy risks.
- These devices present a low risk of serious complications such as pelvic infection.
Keywords:
AdnexitisAge FactorsClinical ResearchContraceptionContraception ContinuationContraceptive EffectivenessContraceptive Methods--side effectsContraceptive UsageCopperDemographic AnalysisDemographic FactorsEvaluationFamily PlanningFertilityFertility MeasurementsIngredients And ChemicalsInorganic ChemicalsIud, Copper Releasing--side effectsIud--side effectsLife Table MethodMenstruation DisordersMetalsPainPopulationPopulation DynamicsPregnancy RateResearch MethodologyUse-effectiveness