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Updated: Jun 25, 2025

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Posterior mitral leaflet cleft in nonobstructive hypertrophic cardiomiopathy
Serenella Conti1, Martina Sordi2, Alessio Arrivi2
1Cardiology Institute -Santa Maria Hospital, Terni, Italy. serenella.conti@gmail.com.
This case study highlights a rare instance of severe mitral regurgitation caused by a posterior mitral leaflet cleft in a patient with hypertrophic cardiomyopathy. Surgical cleft correction successfully resolved the mitral regurgitation, offering a new therapeutic approach.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- Hypertrophic cardiomyopathy (HCM) is a complex cardiac condition.
- Mitral regurgitation (MR) is a common complication of HCM.
- Structural mitral valve abnormalities can contribute to MR severity in HCM.
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